Ketamine HCL, Ketamine hydrochloride  CAS Number: 1867-66-9

Ketamine HCL, Ketamine hydrochloride  CAS Number: 1867-66-9

Ketamine HCL, Ketamine hydrochloride  CAS Number: 1867-66-9

  • Product Name
    Ketamine Hydrochloride
  • Synonyms
    (+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
  • CAS Number
    1867-66-9
  • Appearance
    White Crystals

Ketamine hydrochloride 
CAS Number: 1867-66-9
EC Number: 217-484-6
IUPAC Name: 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride

1. PHYSICAL AND CHEMICAL PROPERTIES
Molecular Formula: C13H16ClNO.HCl
Molecular Weight: 274.19
Physical Appearance: White crystalline
Solubility: water to 100 mM
Storage: Store at RT
Batch Molecular Structure:
2. ANALYTICAL DATA
HPLC: Shows >99.9% purity

Description:
Ketamine hydrochloride is a non-competitive NMDA receptor
antagonist (EC values are 13.6 and 17.6 μM for GluN1/GluN2A
(formally NR1 and NR2A, respectively) and GluN1/GluN2B
(formally NR1 and NR2B, respectively) subunit combinations
respectively). Dissociative anesthetic. S-enantiomer and Active
metabolite also available. Please refer to IUPHAR Guide to
Pharmacology for the most recent naming conventions.

Physical and Chemical Properties:
Molecular Formula: C H ClNO.HCl
Molecular Weight: 274.19
Physical Appearance: White crystalline
Minimum Purity: ≥99%
Batch Molecular Structure:
Storage: Store at RT
Solubility & Usage Info:
water to 100 mM
Stability and Solubility Advice:
Some solutions can be difficult to obtain and can be encouraged
by rapid stirring, sonication or gentle warming (in a 45-60°C
water bath).
Information concerning product stability, particularly in solution,
has rarely been reported and in most cases we can only offer a
general guide. Our standard recommendations are:
SOLIDS: Provided storage is as stated on the product label and
the vial is kept tightly sealed, the product can be stored for up to
6 months from date of receipt.
SOLUTIONS: We recommend that stock solutions, once
prepared, are stored aliquoted in tightly sealed vials at -20°C or
below and used within 1 month. Wherever possible solutions
should be made up and used on the same day.
Other Information:
INFORMATION FOR CUSTOMERS IN THE UK ONLY
This product is a Schedule 2 Home Office controlled substance
and customers in the UK are required to hold the relevant
licence or be exempt from restrictions in order to purchase and
possess this material.

References:
Liu et al (2001) Modulation of NMDA receptor function by KA and magnesium: part I. Anesth.Pharmacol. 92 1173.
Pallares et al (1995) Effects of KA, a noncompetitive NMDA antagonist, on the acquisition of the lever-press response in rats.
Physiol.Behav. 57 389. PMID: 7716221.
Anis et al (1983) The dissociative anaesthetics, KA and phencyclidine, selectively reduce excitation of central mammalian neurones by
N-methyl-aspartate. Br.J.Pharmacol. 79 565. PMID: 6317114.

Remarks: Ketamine HCL is controled by government, if customer want order it, please apply for the Import License in advance, then we take your Import license to apply for the Export License. Buy Ketamine HCL without License is illegal!

 

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