Lidocaine HCL, Lidocaine Hydrochloride
Lidocaine HCL, Lidocaine Hydrochloride
Lidocaine HCL, Lidocaine Hydrochloride, USP/BP/EP
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Product NameLidocaine Hydrochloride
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Synonyms2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride hydrate
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CAS Number6108-05-0
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AppearanceWhite Crystalline Powder
Lidocaine HCl USP/BP/EP CAS No 73-78-9
Lidocaine hydrochloride is an amide local anesthetic with the chemical formula C14H23ClN2O. After blood absorption or intravenous administration, it has obvious excitement and inhibitory biphasic effect on the central nervous system, and there is no precursor excitement. When the blood concentration is low, analgesia and drowsiness will occur, and the pain threshold will increase; as the dose increases , The effect or toxicity is enhanced, and there is anticonvulsant effect at the subtoxic blood concentration.
Functions
The product is a local anesthetic and antiarrhythmic drug. Mainly used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve conduction block. This product can be used for ventricular premature beats and ventricular tachycardia after acute myocardial infarction, and it can also be used for ventricular arrhythmias caused by digitalis poisoning, cardiac surgery and cardiac catheterization. This product is usually ineffective for supraventricular arrhythmias.
Certificated of Analysis
| Items | Standard | Results |
| Character | White or almost white crystalline powder | Complies |
| Identification |
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75.10ºC-77.5ºC Complies Complies Complies |
| Appearance of Solution S | colourless | Complies |
| PH | 4.5-5.5 | 5.08 |
| Sulphated Ash | ≤0.1% | 0.06% |
| Water | 5.5%-7.0% | 6.3% |
| Heavy Metals | ≤5ppm | <5ppm |
| Related Substances | Impurities A≤0.01% Unknown single Impurity≤0.1% Total impurities ≤0.5% |
0.0002% 0.006% 0.025% |
| Assay | 97.5%-101.0% | 99.35% |
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