Liraglutide powder 99% CAS Number: 204656-20-2
FDA/GMP Approved Liraglutide powder 99% CAS Number: 204656-20-2
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Product NameLiraglutide
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CAS Number204656-20-2
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AppearanceWhite to off-white crystalline powder or lumps
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Product name |
Liraglutide |
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Sequence |
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-
Glu-Gly-Gln-Ala-Ala-Lys[N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]- -Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
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CAS No. |
204656-20-2 |
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Molecular Formula |
C172H265N43O51 |
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Molecular Weight |
3751.20 |
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Storage |
2~8℃ |
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Appearance |
White to off-white crystalline powder |
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Test |
Specification |
Results |
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Appearance: |
White to off-white crystalline powder or lumps |
White powder |
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Identity: |
3751.2±1.0 |
3751.1 |
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Purity (By HPLC) : |
Not Less than 98.0%; |
99.51% |
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Residual solvents: |
≤0.25%total; ≤0.1%individual; ≤0.01%CH2CN |
Complies |
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Related Peptide |
Total Impurity ≤ 2.0% Largest Single Impurity ≤ 1.0% |
TI =0.41% LSI =0.25% |
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Peptide Content: |
Not Less than 85.0% |
87.7% |
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Water (K.F.): |
Not more than 5% |
4.2% |
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Acetate acid: |
Not more than 10% |
8.1% |
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Bacterial Endotoxins |
Not more than 50IU/mg |
Complies |
Function and Usage of Liraglutide 204656-20-2
1、 Type 2 diabetes
Liraglutide improves control of blood glucose.It reduces meal-related hyperglycemia
(for 24 hours after administration) by increasing insulin secretion (only) when required by increasing
glucose levels, delaying gastric emptying, and suppressing prandial glucagon secretion.
In common to various degrees with other GLP-1 receptor agonists, liraglutide has advantages over
more traditional therapies for type 2 diabetes:
· Liraglutide acts in a glucose-dependent manner, meaning it will stimulate insulin secretion only
when blood glucose levels are higher than normal, preventing “overshoot”. Consequently, it shows
negligible risk of hypoglycemia.
· Liraglutide has the potential for inhibiting apoptosis and stimulating regeneration of beta cells
(seen in animal studies).
· Liraglutide decreases appetite and inhibits body weight gain, as shown in a head-to-head study
versus glimepiride.
· Liraglutide lowers blood triglyceride levels.
2、Obesity
Liraglutide has been approved as an injectable adjunct to a reduced-calorie diet and increased
physical activity for chronic weight management in adult patients. The specified criteria are an
initial body mass index (BMI) of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater
(overweight), in the presence of at least one weight-related comorbid condition
(e.g.hypertension, type 2 diabetes mellitus, or dyslipidemia). In late 2014, data were reported from
the SCALE™ Obesity and Prediabetes trial, which is a randomised, double-blind, placebo-controlled,
multinational trial in non-diabetic people with obesity and non-diabetic people who are overweight
with comorbidities. In this phase 3a trial, there were 3,731 participants randomised to treatment
with liraglutide 3 mg or placebo, both in combination with diet and exercise. Those who completed
the 56-week trial achieved an average weight loss of 9.2%, to be compared with a 3.5% reduction in
the placebo group.
- Q1 What’s your MOQ?
A:Usually 1 kg，It’s depend on different products. We accept sample order. Also for some
- products we can provide you with free sample.
- Q2 How to control and quality assurance?
a.High grade clean workshop.
b. Inspection center equipped with instruments of HPLC, GC etc, R&D and QC for testing of each batch.
c. Cooperated with third-party test agency for testing heavy metals, pesticide residues, allergen etc.
- Q3 what kind of payment do you support?
T/T, Trade Assurance, Paypal, Western Union,Alipay, Credit Card, L/C etc.
- Q4 What’s your shipping methods and delivery time?
a.Shipping Methods: DHL/Fedex/Air Shipping/Sea Shipping
b.Shipping Time: 3-5 days by air or 7-14 days by sea
- Q5 How to qaurantee the after-sale?
a.We provide 24-hour customer service. If you encounter any product quality problems or transportation
- problems, please feel free to contact us
b.lf any problem happens after sale, either quality or quantity, we will try to solve it instantly.and we even
- have recall system if necessary.
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